Zacualpan may refer to any of the following settlements in Mexico:
- , in the municipality of Comala
- , in the municipality of Atoyac de Álvarez
- Zacualpan, State of Mexico
- Zacualpan de Amilpas, Morelos
- Zacualpan, Nayarit
- San Jerónimo Zacualpan, Tlaxcala
- Zacualpan, Veracruz
Similar names
- Zacualtipán, Hidalgo