X25 may refer to:
- X.25, a telecommunications protocol suite
- X25 (New York City bus)
- Bensen X-25, an American experimental aircraft
- , an X-class submarine
- HP Jornada X25, a PDA manufactured by Hewlett-Packard
- National Express Coach route X25
- Senova X25, a Chinese automobile
See also
- X25-M, a solid-state drive