William Rose may refer to:

Sports

  • William Rose (footballer) (1861–1937), England international footballer
  • William Rose (cricketer, born 1934), former English cricketer
  • William Rose (cricketer, born 1842) (1842–1917), English cricketer
  • Bill Rose (footballer) (1931–2007), Australian rules footballer
  • Bill Rose (swim coach), American swimming coach
  • Billy Rose (curler) (1904–1987), Canadian curler
  • Willie Rose (William Rose, born 1987), American football fullback

Politicians

  • William Rose I (fl. 1393–1406), MP for Weymouth
  • William Rose (MP for Canterbury) (before 1410–after 1443), MP for Canterbury
  • William Oliver Rose (1871–1936), physician and politician in British Columbia, Canada
  • William Stewart Rose (1775–1843), poet, translator, Treasurer of the Navy, Member of Parliament
  • Sir William Rose (Clerk of the Parliaments) (1803-1885), clerk of the Parliaments
  • William Anderson Rose (1820–1881), businessman, MP and Lord Mayor of London
  • William G. Rose (1829–1899), Republican mayor of Cleveland, Ohio
  • William Edward Rose, American hotelier, railroad president and politician in South Carolina
  • William Pinckney Rose (1787–1850), American soldier and participant in the Mississippi Constitutional Convention of 1832.

Others

  • William Rose (schoolmaster and writer) (1719–1786), Scottish schoolmaster and classical scholar
  • William Cumming Rose (1887–1985), American nutritionist
  • William Rose (illustrator) (1909–1972), American film poster illustrator
  • William Rose (screenwriter) (1914–1987), American screenwriter
  • Axl Rose (William Rose, born 1962), Guns N' Roses vocalist
  • William I. Rose (geologist), American mineralogist
  • William I. Rose (United States Army officer) (1898–1954), American military officer
  • Sir William Rose, 2nd Baronet (1846–1902), owner in Victorian times of Moor Park, Farnham
  • William Kinnaird Rose (1845–1919), editor of the Brisbane Courier
  • William John Rose (1885–1968), Canadian Slavist and historian
  • Billy Rose (1899–1966), American theatrical showman
  • William Balthazar Rose (born 1961), British painter