150px|thumb|Coat of Arms of William Drayton, Sr.
William Drayton Sr. (March 21, 1732 – May 18, 1790) was chief justice of the British American Province of East Florida and a United States district judge of the United States District Court for the District of South Carolina.
Education and career
Born March 21, 1732, near the Ashley River in the Province of South Carolina, British America, Drayton graduated from the Middle Temple in London, England in 1754 and read law in 1756. He was a Judge of the South Carolina Admiralty Court in 1789.