Wilkes may refer to:
Places
- Wilkes, Portland, Oregon, a US neighborhood
- Wilkes County, Georgia
- Wilkes County, North Carolina
- Wilkes Basin, George V Land, Antarctica
- Wilkes Station, Antarctica, a research station
- Battery Wilkes, a historic artillery battery in West Ashley, Charleston, South Carolina
- Wilkes Power Plant, Jefferson, Texas, an electrical power station
- Wilkes Island, islet of Wake Island in the Central Pacific.
Schools in the United States
- Wilkes University, Pennsylvania
- Wilkes Community College, Wilkesboro, North Carolina
- Wilkes Honors College, Florida
People
- John Wilkes, English radical journalist and politician in the late 18th century.
- Wilkes (surname), other people with the surname
- Wilkes Angel (1817–1889), New York lawyer and politician
- Wilkes C. Robinson (1925–2015), judge of the United States Court of Federal Claims from 1987 to 1997
Other uses
- , several US Navy vessels
- Wilkes (horse) (born 1952), Australian thoroughbred
See also
- Wilk
- Wilken
- Wilkens
- Wilkes Land, Antarctica
- Clarie Coast, called Wilkes Coast in Australia
- Wilkes-Barre, Pennsylvania, a city
- Wilkes-Barre Township, Luzerne County, Pennsylvania
- Wilkes-Barre Variation, a chess opening
- Wilks (disambiguation)