Wellsville is a borough in York County, Pennsylvania, United States. The population was 299 at the 2020 census.

thumbtime=33|thumb|left|upright=1.1|A Walk up Main Street (video - 3 minutes)

Because of its unusually high quality of preservation, nearly all of the community was placed on the National Register of Historic Places in 1977 as the "Wellsville Historic District".

According to the United States Census Bureau, the borough has a total area of , all land.

Demographics

As of the census