Wapello is a city in and the county seat of Louisa County, Iowa, United States. The population was 2,084 at the time of the 2020 census.
Wapello is part of the Muscatine Micropolitan Statistical Area.
History
Wapello was platted in the late 1830s.
The city's namesake is Wapello, a Meskwaki chief.
Geography
Wapello is located on the west side of the Iowa River. US Route 61 passes through the community.
thumb|Aerial View Wapello, IowaAccording to the United States Census Bureau, the city has a total area of , of which is land and is water.