WGS may refer to:
Education
- Women's and Gender Studies, a field of study at universities worldwide
Schools
- Wisbech Grammar School, an independent school in Cambridgeshire, England
- Withington Girls' School, a girls' school in Fallowfield, Manchester, England
- Wolverhampton Grammar School, an independent school in Wolverhampton, England
Science and technology
- Whole genome sequencing, a laboratory process that determines the complete DNA sequence of an organism's genome at a single time
- World Geodetic System, a reference frame for the earth for use in geodesy and navigation
- Wideband Global SATCOM, a United States and Australian military communication satellite system
- Water gas shift reaction, a chemical reaction of carbon monoxide and water vapor into carbon dioxide and hydrogen
Other
- Watergardens railway station, Melbourne
- World Gourmet Summit, a food festival
- World Group Securities, the broker-dealer affiliate of World Financial Group (WFG) and a member of AEGON Group