WCU may stand for:
- West Chester University, one of the 14 state universities of the Pennsylvania State System of Higher Education
- West Coast University, for-profit college headquartered in California
- Western Carolina University, Cullowhee, North Carolina, a constituent campus of the University of North Carolina system
- Western Colorado University
- Working Class Union, an early 20th century organization most notably associated with the Green Corn Rebellion
- World currency unit