Vespucci may refer to:
People
Surname
- Agostino Vespucci of Florence
- Amerigo Vespucci, Italian explorer, assistant of Christopher Columbus and after whom the American continent was named.
- Simonetta Vespucci, Italian Renaissance noblewoman from Genoa
Other uses
- Ponte Amerigo Vespucci, a bridge over the Arno River in Florence, Italy
- Italian training ship Amerigo Vespucci, a tall ship of the Italian Navy
- Vespucci, a map editing program for OpenStreetMap