Van de Wetering is a Dutch toponymic surname, meaning "from/of the (drainage) channel". Among spelling variants are Watering, Weetering and Weteringh. Many waters in the Netherlands have the name as well a number of towns, themselves named after a wetering, e.g. Wetering, Nieuwe-Wetering, Nieuwe-Wetering, and Oude Wetering. Forms without the article (Van Wetering etc.) likely refer to such a settlement. People with these names include:
;Van de Wetering
- Ernst van de Wetering (1938–2021), Dutch Rembrandt expert
- Henricus van de Wetering (1850–1929), Dutch archbishop
- Janwillem van de Wetering (1931–2008), Dutch–American author of detective novels
- Marlon van de Wetering (born 2007), Jamaican footballer
- Peter Van de Wetering (1931–2014), Dutch–American horticulturist
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- Bo van Wetering (born 1999), Dutch handball player
- Ineke van Wetering (1934–2011), Dutch anthropologist and Surinamist
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- (1929–2017), Dutch ballet dancer and choreographer
- Myrthe van de Weetering (born 1988), Dutch violinist and composer