Upham may refer to:
Places
- Upham, Hampshire, England
- Upham, New Mexico
- Upham, North Dakota
- Upham, Wisconsin, named for Governor William H. Upham
- Upham Mansion, Marshfield, Wisconsin, his home
- Upham Parish, New Brunswick
- Upper Upham, Wiltshire, England
People
- Upham (surname)
Ships
- USS Upham (DE-283), a United States Navy destroyer escort converted during construction into the high-speed transport USS Upham (APD-99)
- USS Upham (APD-99), a United States Navy high-speed transport in commission from 1945 to 1946