Upfield is a word with several meanings:
- Upfield (company), a margarine and food spreads company, derived from margarine division of Unilever
- Upfield, Victoria, a suburb of Melbourne, Australia
- Upfield railway station
- Upfield railway line
- Upfield bike path
- Arthur Upfield (1890–1964), a detective novelist
- "Upfield", a song by Billy Bragg from the album William Bloke (1996)