USS S-49 (SS-160) was a fourth-group (S-48) S-class submarine of the United States Navy.
Construction and commissioning
S-49s keel was laid down on 22 October 1920 by the Lake Torpedo Boat Company in Bridgeport, Connecticut. She was launched on 23 April 1921, sponsored by Mrs. Joseph E. Austin, and commissioned at Bridgeport on 6 June 1922 with Lieutenant Ingram C. Sowell in command.
Service history
S-49 remained at Bridgeport through July 1922, but in August 1922 she moved down to the Submarine Base at New London, Connecticut, where she joined Submarine Division Zero, composed of units engaged in submarine research and development.