USS Renshaw (DD/DDE-499), a , was the third ship of the United States Navy of that name, in honor of Commander William B. Renshaw.

Renshaw was laid down 7 May 1942 by the Federal Shipbuilding & Drydock Company in Kearny, New Jersey; launched on 13 October 1942, sponsored by Miss Dorothy Lillian Renshaw; and commissioned on 5 December 1942.

South Pacific, 1943–1944

Following shakedown, Renshaw reported to the Pacific Fleet in the spring of 1943, and protected transports in the Solomon Islands area. On 2 July 1943, she participated in the bombardment of the Vila Stanmore and Shortland Island areas in Kula Gulf, coming under the fire of enemy shore batteries.

From 21 to 25 November, she pounded East Island in Empress Augusta Bay with 200 rounds of 5 inch ammunition. Sorum and Makatawa on northeast Bougainville next felt her blows, and she then proceeded north of Buka Island for an offensive sweep between Buka and Green Islands. On the morning of 20 January, she retired southward with her task unit to give fire support to the landings on Bougainville Island itself.

During landings in the New Britain-New Ireland area, Renshaw dealt considerable damage to enemy airfield installations while coming under the fire of shore batteries. On 13 March the ship was in the Empress Augusta Bay area where she bombarded enemy positions in the jungles east of the beachhead held by Allied forces.

After a short period of amphibious training at Pearl Harbor, Renshaw led a force of LSTs to the Marianas Islands. At first assigned to the outer destroyer screen, she later closed the Tinian beach to provide star shell illumination and fire support for troops ashore who were undergoing a heavy counterattack.

Philippines, 1944–1945

In November 1944, while operating with a destroyer division bombarding enemy installations in the Ormoc Bay area and conducting anti-shipping sweeps in the waters westward of Leyte, Renshaw spotted on the surface. Renshaw and accompanying destroyers , , and