Two ships of the United States Navy have borne the name USS Pickerel, named for the pickerel, a young or small pike.
- The first, , was a Porpoise-class submarine, launched in 1936 and lost in 1943 under unknown circumstances.
- The second, , was a , launched in 1944 and stricken in 1977.
A third ship, , was originally laid down as USS Pickerel, but renamed prior to her 1912 launch.