USS John Paul Jones refers to two destroyers of the United States Navy, named after John Paul Jones:
- , a Forrest Sherman-class destroyer, commissioned in 1956, redesignated as DDG-32 in 1967, and decommissioned in 1982
- , an Arleigh Burke-class guided missile destroyer, commissioned in 1993, and in active service as of 2024
See also
- , three earlier United States Navy warships named after John Paul Jones.