UPR may refer to:

  • Unfolded protein response, a biological response in the "endoplasmic reticulum" when some proteins did not properly fold
  • Union Pacific Railroad, a freight railroad based in Omaha, Nebraska.
  • Universal Periodic Review of the United Nations Human Rights Council
  • Unconditional positive regard, one of the three core conditions of "person-centered therapy"
  • Utah Public Radio, a radio station, part of the College of Humanities and Social Sciences at Utah State University

Politics

  • Unia Polityki Realnej, a political party in Poland
  • Popular Republican Union (disambiguation) (French: Union Populaire Républicaine, UPR)
  • Progressive Union for Renewal (, UPR), a political party in Benin
  • Union for Progress and Renewal, a political party in Guinea
  • Ukrainian People's Republic (1917–21), former state in Eastern Europe
  • Unitary parliamentary republic, a form of unitary states

University

  • University of Palangka Raya, the public university in Palangkaraya, Indonesia
  • University of Puerto Rico, the public university system of Puerto Rico, or one of its 11 campuses:
  • University of Puerto Rico, Medical Sciences Campus
  • University of Puerto Rico at Aguadilla
  • University of Puerto Rico at Arecibo
  • University of Puerto Rico at Bayamón
  • University of Puerto Rico at Carolina
  • University of Puerto Rico at Cayey
  • University of Puerto Rico at Humacao
  • University of Puerto Rico at Mayagüez
  • University of Puerto Rico at Ponce
  • University of Puerto Rico at Rio Piedras
  • University of Puerto Rico at Utuado