Tuscaloosa is the name of two places in the United States of America, named after the Native American chief, Tuskaloosa:
- Tuscaloosa, Alabama
- Tuscaloosa County, Alabama
Music
- Tuscaloosa (album), a 2019 live album by Neil Young and the Stray Gators
Film
- Tuscaloosa (film), a 2019 American film starring Natalia Dyer
U.S. military vessels
- USS Tuscaloosa (CA-37), U.S. Navy New Orleans-class heavy cruiser
- USS Tuscaloosa (LST-1187), U.S. Navy Newport-class of tank landing ships (LST)