TPN may refer to:
Science and Medicine
- Total parenteral nutrition
- Triphosphopyridine nucleotide, the previous name for nicotinamide adenine dinucleotide phosphate (NADP<sup>+</sup>)
- Task Positive Network, see Dorsal attention network
Organisations
- Society of Friends of Science in Warsaw () in Warsaw
- Tatra National Park, Poland ()
Other
- Third-party note or Note verbale, a diplomatic document
- Tupinambá language, by ISO 639 code
- Tiputini Airport, Ecuador
- Treaty on the Prohibition of Nuclear Weapons
- "The Promised Neverland" (Manga / Anime Series)
