TCA may refer to:

Chemistry and biochemistry

  • Toxin complex a, an insecticidal toxin complex produced by Photorhabdus luminescens bacteria
  • Tricarboxylic acid cycle, an alternate name for the citric acid cycle pathway in cellular metabolism
  • Trichloroacetic acid, chemical used to precipitate protein in serum
  • 2,4,6-Trichloroanisole, cause of cork taint in wine
  • Tricyclic antidepressant, a class of medications
  • TCA, a codon for the amino acid serine

Culture and media

  • Taiwanese Cultural Association
  • Tekeyan Armenian Cultural Association, a network of Armenian cultural organisations
  • Television Critics Association
  • The Canadian Amateur, radio amateur magazine
  • Tribune Content Agency, a syndication company owned by Tribune Publishing
  • Triple Crown of Acting is a term used in the American entertainment industry to describe actors who have won a competitive Academy Award, Emmy Award, and Tony Award in the acting categories
  • Twentieth Century Animation, the animation division of 20th Century Studios

Economics and finance

  • Transaction cost analysis
  • Total cost of acquisition
  • True cost accounting

Education

  • The Classical Academy (Colorado), Colorado Springs, US
  • Trinity Christian Academy (Deltona, Florida), US
  • Trinity Christian Academy (Jackson, Tennessee), US

Organizations

  • Taipei Computer Association
  • The Consulting Association
  • Total Community Action
  • Trans-Canada Air Lines, predecessor to Air Canada
  • Train Collectors Association
  • Transportes Carga Aérea, a defunct Brazilian airline

Politics

  • Taiwan Constitution Association, a political party in Taiwan
  • EU–UK Trade and Cooperation Agreement, between the UK and the EU (2020)
  • The Competition Authority (Ireland) (2002–2014)

Other uses

  • Terminal control area, a volume of controlled airspace
  • Topology change acknowledgement, a message in the 802.1D Spanning Tree Protocol (STP)
  • Transportation Corridor Agencies, a toll road authority in Orange County, California
  • Traumatic cardiac arrest, due to trauma
  • Tennant Creek Airport, IATA airport code "TCA"
  • Turks and Caicos Islands, country code
  • Tropical Cyclone Advisory, tropical forecast service for international aviation safety