Stephano may refer to:
;Fictional characters
- Stephano (The Tempest), a drunkard in Shakespeare's The Tempest
- An alias of Count Olaf in Lemony Snicket's A Series of Unfortunate Events
;Other
- Stephano (moon), a natural satellite of the planet Uranus
- SS Stephano, a ship
See also
- Stefano, an Italian name
- Stephanos, a Greek given name