right|thumb|The previous courthouse as it appeared in 1878.
Schuyler County is a county located in the northeastern portion of the U.S. state of Missouri. As of the 2020 census, its population was 4,032, making it the fourth-least populous county in Missouri. Its county seat is Lancaster. The county was organized February 14, 1845, from Adair County, and named for General Philip Schuyler, delegate to the Continental Congress and U.S. Senator from New York.
Schuyler County is part of the Kirksville, MO Micropolitan Statistical Area.
, a World War II-era cargo ship, was named in part for Schuyler County, Missouri.
Geography
According to the U.S. Census Bureau, the county has a total area of , of which is land and (0.3%) is water. It is the second-smallest county in Missouri by area. Schuyler County borders Iowa to the north.
Adjacent counties
- Appanoose County, Iowa (northwest)
- Davis County, Iowa (northeast)
- Scotland County (east)
- Adair County (south)
- Putnam County (west)
Major highways
- 20px U.S. Route 63
- 20px U.S. Route 136
- 20px Route 202