Santo António da Serra ( of the mountain) is a civil parish in the interior of the municipality of Machico, on the island of Madeira. The parish is adjacent to another parish in the neighbouring municipality of Santa Cruz to the south, which is also named Santo António da Serra. The population in 2011 was 1,617, in an area of 8.62 km<sup>2</sup>.
History
235px|left|thumb|Historical implements seen at the Apple Festival in Santo da Serra The parish name originated from the local adoration of Saint Anthony, and the name usually shortened to Santo da Serra in conversation.
Settlement of this region happened late, owing to most settlers' preference for coastal lands rather than the rugged interior. It is likely to have occurred during the 16th century, beginning in the area of the parochial church, and progressed to a point where Gil de Carvalho ordered the construction of two chapels for the resident population.