Sandusky may refer to:
Places in the United States
Cities and towns
- Sandusky, Indiana
- Sandusky, Iowa
- Sandusky, Michigan
- Sandusky, Ohio
- Upper Sandusky, Ohio
- Sandusky, West Virginia
- Sandusky, Wisconsin
Townships
- Sandusky Township, Crawford County, Ohio
- Sandusky Township, Richland County, Ohio
- Sandusky Township, Sandusky County, Ohio
County
- Sandusky County, Ohio
River
- The Sandusky River in Ohio
Other uses
- Sandusky (surname), a surname
- Sandusky (locomotive), the first locomotive to operate in Ohio
- Sandusky (automobile company), 1902–1904 automobile manufacturer in Ohio
- Sandusky District, a railroad line in Ohio
- Sandusky High School, a secondary school in Sandusky, Ohio
- Sandusky House (Lynchburg, Virginia), a historic home
- Sandusky station, a Sandusky, Ohio, Amtrak station built in 1892