Sancti Spiritus (Latin genitive, 'of the holy spirit') or Sancti Spiritu may refer to:
Places
- Sancti-Spíritus, Badajoz, Spain
- Sancti-Spíritus, Salamanca, Spain
- Sancti Spíritus, Cuba
- Sancti Spíritus Province
- Sancti Spíritus Airport
- Sancti Spiritu (Argentina), a 1527 fortification
Other uses
- Sancti Spiritus (cigar)
- FC Sancti Spíritus, a Cuban football club, based in Sancti Spíritus
- Sancti Spíritus (baseball), Cuba
See also
- Espírito Santo (disambiguation)
- Espiritu Santo (disambiguation)
- Holy Spirit (disambiguation)
- Santo Spirito (disambiguation)
- Spiritus Sanctus Academies
- Spiritus sancti gratia