Salvinorins are a group of natural chemical compounds and their structural analogs. Several salvinorins have been isolated from Salvia divinorum. They are classified as diterpenoid furanolactones. Salvinorin A is a hallucinogen with dissociative effects.
Several salvinorins have been isolated and characterized.
{| class="wikitable" style="text-align:center"
|+ Natural salvinorins
|- class="backgroundcolor5"
! Name !! Structure !! R<sup>1</sup> !! R<sup>2</sup> !! Chemical formula !! Molar mass !! CAS number !! PubChem
|-
| Salvinorin A || rowspan=2 | 120px|right || –OCOCH<sub>3</sub> || − || C<sub>23</sub>H<sub>28</sub>O<sub>8</sub> || 432.46 g·mol<sup>−1</sup> || 83729-01-5 ||
|-
| Salvinorin B || –OH || − || C<sub>21</sub>H<sub>26</sub>O<sub>7</sub> || 390.43 g·mol<sup>−1</sup> || 92545-30-7 ||
|-
| Salvinorin C || rowspan=6 | 120px|right || –OCOCH<sub>3</sub> || –OCOCH<sub>3</sub> || C<sub>25</sub>H<sub>30</sub>O<sub>9</sub> || 475.29 g·mol<sup>−1</sup> || 385785-99-9 || –
|-
| Salvinorin D
- Salvia absconditiflora (salvinorin A at 51.5 μg/g, and salvinorin B at 402.2 μg/g) Salvinorin B methoxymethyl ether is seven times more potent than Salvinorin A at KOPr in GTP-γS assays.
Many other terpenoids have been isolated from Salvia divinorum, including classes named divinatorins and salvinicins. None of these compounds have shown significant (sub-micromolar) affinity at the kappa-opioid receptor, and there is no evidence that they contribute to the plant's psychoactivity.
