Saint Eusebius may refer to:
- Pope Eusebius, Pope 309–310.
- Eusebius of Cremona (died )
- Eusebius of Fano (died )
- Eusebius of Gaza (died )
- Eusebius of Rome (died ), priest and martyr
- Eusebius of Samosata (died ), bishop of Samosata
- Eusebius of Vercelli (–381), bishop of Vercelli