Saikyo may refer to:
- Saikyō Line, a Japanese railway line in the Tokyo metropolitan area
- Saikyō Maru, a Japanese ship involved in the Battle of the Yalu River (1894)
- Western Capital (disambiguation) (), several topics
- Psikyo (), a Japanese game developer
People with the surname Saikyo include:
- Haruma Saikyo (born 1998), Japanese kickboxer
- Yuma Saikyo (born 2000), Japanese kickboxer