STS-40, the eleventh launch of Space Shuttle Columbia, was a nine-day mission in June 1991. It carried the Spacelab module for Spacelab Life Sciences 1 (SLS-1), the fifth Spacelab mission and the first dedicated solely to biology. STS-40 was the first spaceflight that included three women crew members.
Crew
Crew seat assignments
{| class="wikitable" style="text-align:center"
!Seat
!Launch
!Landing
|rowspan=8| 150px<br />Seats 1–4 are on the flight deck.<br />Seats 5–7 are on the mid-deck.
|-
!1
| colspan="2" |O'Connor
|-
!2
| colspan="2" |Gutierrez
|-
!3
|Bagian
|Seddon
|-
!4
| colspan="2" |Jernigan
|-
!5
|Seddon
|Bagian
|-
!6
|colspan=2| Gaffney
|-
!7
|colspan=2| Hughes-Fulford
|}