Roxanne may refer to:

  • Roxanne (given name)
  • Hurricane Roxanne, a major hurricane in October 1995

Music

  • "Roxanne" (The Police song), a 1978 song by The Police
  • "Roxanne" (Arizona Zervas song), a 2019 song by Arizona Zervas
  • "Roxanne", a 1978 song by Golden Earring from Grab It for a Second
  • Roxanne (band), a band active in the late 1980s

Films

  • Roxanne (film), a 1987 movie adaptation of the play Cyrano De Bergerac with Steve Martin and Daryl Hannah
  • Roxanne Roxanne, a 2017 American film

Other

  • Roxanne (Pokémon), a character in the Pokémon universe
  • Roxanne (model) (1929–2024), American actress and game show assistant

See also

  • Roxane (disambiguation)
  • Roxan, a protein that in humans is encoded by the ZC3H7B gene
  • Roxann
  • Roxana (disambiguation), one of Alexander the Great's wives
  • Roxelana, one of Suleiman the Magnificent's wives
  • Roshanak, the usual Western spelling of the Persian feminine name
  • Roxanne Wars, a series of hip-hop rivalries in the 1980s
  • Roxy (disambiguation)