RPO may refer to:
Business
- Recovery point objective, in business-continuity planning for computing
- Recruitment process outsourcing, a form of business-process outsourcing
- Regular Production Option, a General Motors standard coding system
Military
- Regulating Petty Officer, a rate (rank) in the Royal Navy Police
- RPO-A Shmel (Bumblebee), a grenade launcher produced by Russia
Music
- Rochester Philharmonic Orchestra, an orchestra in New York State
- Royal Philharmonic Orchestra, an orchestra in London, England
Science and technology
- Recursive path ordering, a well-ordering in term rewriting (computer science)
- Research Performing Organisations, a term used in European science policy
Sports
- Runs per over or run rate, a measure in the game of cricket
- Run-pass option, an offensive scheme in American football
Other
- Railway post office, a mobile post office set up in a railway car
- Retail Post Outlet, a Canadian postal abbreviation
- Revenue Protection Officer, a UK railway employee who issues penalty fares
- Rzecznik Praw Obywatelskich, a Polish ombudsman