RPI may refer to:
Universities
- Rensselaer Polytechnic Institute, Troy, New York, US
- Richmond Professional Institute, merged into Virginia Commonwealth University
Science and technology
- Raspberry Pi (RPi), single-board computers and microcontrollers by public traded Raspberry Pi Ltd.
- Reticulocyte production index, a blood test result
- Ribose-5-phosphate isomerase (Rpi), an enzyme
Organizations
- Recognition Professionals International
- Republican Party of India
- Republican Party of Iowa
- Regenerative Pelvic Institute
- Reputation Poll International
Other
- Rating percentage index, in college sports
- Retail price index, UK inflation measure
- Revenue Protection Inspector, on UK public transport
- Rock progressivo italiano, Italian progressive rock
See also
- RP 1 (disambiguation)
- RPL (disambiguation)