RPF may refer to:
Computing
- Raster Product Format, a GIS file format
- Reverse-path forwarding, a technique in multicast routing in networking
- Reverse power feeding, in broadband networking
Medicine
- Renal plasma flow, a metric of the volume of blood delivered to the kidneys
- Retroperitoneal fibrosis, a disease of the retroperitoneum
Military
- Railway Protection Force, a paramilitary organization for railways in India
- Rohingya Patriotic Front, a Rohingya group active in the 1970s and 80s in Bangladesh
- (Rpf.), unit of the German
Political parties
- , France (1947–1955), a Gaullist party
- , France (1999–2011), a right wing party
- , Netherlands (1975–2003), a Protestant Christian party
- Rwandan Patriotic Front, Rwanda (founded 1994), a major political party backed by Paul Kagame
Other uses
- Radioisotope Production Facility, a facility in Inshas, Egypt
- Real person fiction, a genre of fanfiction about real people
- Rehabilitation Project Force, a Scientology program