thumb|right|300px|The R46 between Riebeek-Kasteel and [[Malmesbury, Western Cape|Malmesbury]]
The R46 is a provincial route in Western Cape, South Africa that connects Malmesbury with Touws River, via Riebeek-Kasteel, Tulbagh and Ceres. The R46 is co-signed with the R44 between Gouda and Hermon in the Berg River valley.
Route
The R46 begins at a junction with the R45 road about 4 kilometres east of Malmesbury. It begins by heading east-north-east for 15 kilometres to Riebeek-Kasteel, where it meets the southern terminus of the R311 road (which provides access to the town centre). The R46 proceeds south-east for 10 kilometres to cross the Berg River and reach a T-junction with the R44 route in the town of Hermon.