R16 may refer to:

Roads

  • R16 road (Ghana)
  • R-16 regional road (Montenegro)

Vehicles

  • R16 (New York City Subway car)
  • Lublin R-XVI, a 1932 Polish passenger and air ambulance aircraft
  • Renault 16, a family hatchback
  • Romano R.16, a high wing monoplane
  • , a destroyer of the Royal Canadian Navy
  • , an aircraft carrier of the Royal Navy
  • , a submarine of the United States Navy

Other uses

  • R-16 or Restricted-16, a movie rating from the Movie and Television Review and Classification Board
  • R-16 (missile), a Soviet intercontinental ballistic missile
  • R16 (Rodalies de Catalunya), a regional rail line in Catalonia, Spain
  • Aika R-16: Virgin Mission, an anime OVA series
  • R-16 Korea, an international b-boy competition
  • R16: Explosive when mixed with oxidising substances, a risk phrase
  • Small nucleolar RNA R16