Putumayo may refer to:
- Putumayo Department, Colombia
- Putumayo Province, Loreto Region, Peru
- Putumayo District, Putumayo Province, Loreto Region, Peru
- Putumayo Canton, Ecuador
- Putumayo River or Içá River, a river in South America
- Putumayo World Music, an American record label
- Putumayo, a fictional store in the Seinfeld episode "The Millennium"
See also
- Potemayo, Japanese manga and anime series