Panama is divided into ten provinces () and four provincial-level indigenous regions (Spanish: comarcas indígenas, often shortened to comarcas). The most recently established province is Panamá Oeste Province on 1 January 2014, and the most recently established indigenous region is Naso Tjër Di Comarca on 4 December 2020.
There are also two indigenous regions within provinces that are considered equivalent to a corregimiento (municipality).
List of provinces
{| class="wikitable sortable"
|-
! Flag
! Province
! Capital
! Area (km<sup>2</sup>)
! Population<br />(2023 census)
! Population density<br />(2023, per km<sup>2</sup>)
|-
| 45px
| Bocas del Toro
| Bocas del Toro
| 4,654.0
| 159,228
| 125,461
| 34.2
|-
| 45px
| Chiriquí
| David
| 6,584.2
| 471,071
| 416,873
| 71.5
|-
| 45px
| Coclé
| Penonomé
| 4,943.0
| 268,264
| 233,708
| 54.3
|-
| 45px
| Colón
| Colón
| 4,605.0
| 281,956
| 241,928
| 61.2
|-
| 45px
| Darién
| La Palma
| 12,402.7
| 54,235
| 48,378
| 4.4
|-
| 45px
| Herrera
| Chitré
| 2,362.9
| 122,071
| 109,955
| 51.6
|-
| 45px
| Los Santos
| Las Tablas
| 3,812.0
| 98,466
| 89,592
| 25.8
|-
|
| Panamá
| Panama City
| 8,478.5
| 1,439,575
| 1,249,032
| 169.8
|-
| 45px
| Panamá Oeste
| La Chorrera
| 2,892.1
| 653,665
| 464,038
| 226.2
|-
| 45px
| Veraguas
| Santiago de Veraguas
| 10,597.5
| 259,791
| 226,991
| 24.5
|}
Indigenous regions (comarcas indígenas)
Provincial level
{| class="wikitable sortable"
|-
! Flag
! Comarca
! Capital
! Area (km<sup>2</sup>)