Portales may refer to:
People
- Amanda Portales (born 1961), Peruvian artist
- Diego Portales (1793–1837), Chilean politician
- Javier Portales (1937–2003), Argentine actor
- Juan Antonio Portales (born 1996), Mexican footballer
- Suceso Portales (1904–1999), Spanish activist
Places
- Portales, New Mexico, a city in the United States
- Portales Forest Reserve, in New Mexico
Other uses
- Diego Portales University, a Chilean University
- Portales metro station, in Mexico City
- Portales Municipal Airport, an airport of the United States