Port Hope may refer to:
- Port Hope, Michigan, U.S.
- Port Hope, Ontario, Canada
- Port Hope (Peter's Field) Aerodrome
- Port Hope Conference
- Port Hope Panthers
- Port Hope railway station
- Port Hope Transit
- Trenton Golden Hawks, formerly the Port Hope Predators
- Port Hope Simpson, Newfoundland and Labrador, Canada
- Port Hope Simpson Airport
- Port Hope Township, Beltrami County, Minnesota, U.S.