Pope Anastasius II (died 19 November 498) was the bishop of Rome from 24 November 496 to his death on 19 November 498. He was an important figure in trying to end the Acacian schism, but his efforts resulted in the Laurentian schism, which followed his death. Anastasius was born in Rome, the son of a priest, and is buried in St. Peter's Basilica.
Upon being named pope, Anastasius II immediately sent two bishops to Constantinople to meet with the Byzantine Emperor Anastasius I, who had the same name as the pope, and work on an agreement to end the Acacian schism.
During the medieval period, Anastasius II was often considered a traitor to the Catholic Church and an apostate. The writer of the Liber Pontificalis, supporting the opponents to Anastasius' efforts, argued that Anastasius II's death was divine retribution and that he had broken with the church. Similarly, the Decretum Gratiani writes of the pope that "Anastasius, reproved by God, was smitten by divine command." This medieval view is described by modern commentators as a "legend", and "manifestly unjust."
Anastasius II is, with Pope Liberius, one of only two of the first 50 popes not to be canonized.