Pixley may refer to:

;Placenames

  • Pixley, California, USA
  • Pixley, Kansas, USA
  • Pixley, Herefordshire, England
  • Pixley, Shropshire, England
  • Pixley, Wyoming, USA
  • Pixley (Green Acres), fictional place in USA

;Surname

  • Pixley (surname)

;Given Name

  • Pixley ka Isaka Seme (1881-1951), a founder and President of the African National Congress