Patrol torpedo boat PT-41 was a of the United States Navy, built by the Electric Launch Company of Bayonne, New Jersey. The boat was laid down as Motor Boat Submarine Chaser PTC-21, but was reclassified as PT-41 prior to its launch on 8 July 1941, and was completed on 23 July 1941.

After MacArthur's party left Mindanao, PT-41, along with the two remaining PT boats of the squadron (PT-34 and PT-35), established a new base of operations at Cagayan de Oro, Mindanao, supporting the American military forces defending Mindanao and the nearby islands from the invading Japanese throughout late March and early April 1942.

After a torpedo attack in concert with on the on 9 April 1942, PT-41 became the last remaining PT boat of the squadron (PT-34 was sunk in the aftermath of the attack and PT-35 was burned at Cebu). With no more torpedoes available for PT-41 to use, it was commandeered by the United States Army to patrol Lake Lanao, Mindanao. It was destroyed by the Army on 15 April 1942, to prevent its capture while being transported via road to Lake Lanao.