Panjshir may refer to:
- Panjshir Province, a province in northeastern Afghanistan
- Panjshir Valley, a valley in Panjshir Province, near the Hindu Kush mountain range
- Panjshir River, a river in the Panjshir Valley
- Panjshir offensives (Soviet–Afghan War) (1980–1985), series of battles in the Panjshir Valley between the Soviets and the Afghan mujahideen under Ahmad Shah Massoud
- Panjshir Front, Afghan mujahideen under Ahmad Shah Massoud in the Panjshir Valley during the Soviet–Afghan War (1979–1989)
- Panjshir conflict or the Republican insurgency in Afghanistan (2021–), insurgency in the Panjshir Valley against the Taliban government
- National Resistance Front of Afghanistan or Panjshir resistance, anti-Taliban alliance in the Panjshir Valley leading the Republican insurgency
- Panjshir University, university in Panjshir Province, Afghanistan
See also
- Ahmad Shah Massoud, known as the "Lion of Panjshir", Afghan military leader and politician