The Pampanga River is the second largest river on the island of Luzon in the Philippines (next to the Cagayan River) and the country's fifth longest river. It is in the Central Luzon region and traverses the provinces of Pampanga, Bulacan, and Nueva Ecija.

Topography

Its headwaters are at the Sierra Madre and runs a south and southwesterly course for about until it drains into Manila Bay.

The river's basin covers an area of ,