PTL may refer to:
- Panther Lake, Core Ultra Series 3 mobile processors developed by Intel
- Paschall Truck Lines
- Pittsburgh Today Live, program on KDKA-TV
- Point Lookout, New York
- Propositional temporal logic (Linear temporal logic)
- "PTL", a song by Relient K from the album Collapsible Lung
- PTL Satellite Network
- The PTL Club, a former television program