PRF may refer to:
Science and technology
- Physical register file, in CPU design
- Platelet rich fibrin
- Pontine reticular formation
- Positive-real function in mathematics
- Programmed ribosomal frameshifting during mRNA translation
- Pseudorandom function family
- Pulse repetition frequency
Organizations
- Polícia Rodoviária Federal, the Federal Highway Police of Brazil
- Progeria Research Foundation
Business
- Pasture, rangeland, and forage insurance, a type of crop insurance for livestock growers
Other uses
- Perfect (grammar), a tense