Oxycodone/paracetamol,<!-- NOTE: DO NOT CHANGE TO ACETAMINOPHEN, per WP:TITLE --> sold under the brand name Percocet among others, is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain.
History
The United States Food and Drug Administration (FDA) first approved oxycodone/paracetamol in 1976, under application ANDA 085106.
Society and culture
Percocet is often called perc for short. Since the early 2010s, the medication has commonly been name-dropped in songs from multiple genres, such as Future's 2017 song "Mask Off". be limited in their sales because of their contributions to an alleged 400 acetaminophen-related deaths in the U.S. each year, that were attributed to acetaminophen overdose and associated liver damage.
In December 2009, a study found a fivefold increase in oxycodone-related deaths in Ontario, Canada (mostly accidental) between 1991 and 2007; this led to a doubling of all opioid-related deaths in Ontario over the same period.