Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders.
- Mastocytosis
- Skeletal fluorosis
- Monoclonal IgM Kappa cryoglobulinemia
- Hepatitis C.
Hereditary osteosclerosis
- Malignant infantile osteopetrosis
- Neuropathic infantile osteopetrosis
- Infantile osteopetrosis with renal tubular acidosis
- Infantile osteopetrosis with immunodeficiency
- IO with leukocyte adhesion deficiency syndrome (LAD-III)
- Intermediate osteopetrosis
- Autosomal dominant osteopetrosis (Albers-Schonberg)
- Pyknodysostosis (osteopetrosis acro-osteolytica)
- Osteopoikilosis (Buschke–Ollendorff syndrome) providing ballast as an adaptation for an aquatic lifestyle. It makes bones heavier, but also more fragile. In those animal groups, osteosclerosis often occurs together with bone thickening (pachyostosis). This joint occurrence is called pachyosteosclerosis.
See also
- Axial osteomalacia
- Pachyostosis
- Pachyosteosclerosis
- Heinrich Albers-Schönberg