The Order of Mapungubwe is a South African civilian honour awarded by the President of South Africa. It recognises South African citizens whose achievements have international impact and serve the interests of South Africa. It is South Africa's highest honour.

The order is named after the ancient civilisation of Mapungubwe, which was located in modern-day South Africa.

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!scope="row"|Hendrik J. Koornhof

|Silver

|2009

|Biomedical science

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!scope="row"|Fulufhelo Nelwamondo

|Silver

|2017

|Science, especially electrical engineering

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!scope="row"|Siyabulela Xuza

|Silver

|2017

|Scientific innovation

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!scope="row"|Vhahangwele Masindi

|Silver

|2023

|Environmental sciences and water

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!scope="row"|Salim Abdool Karim

|Gold

|2026

| Medical research – tuberculosis and HIV/AIDS

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!scope="row"|Tulio de Oliveira

|Gold

|2026

|Medical research – Omicron variant of COVID-19

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!scope="row"|Keertan Dheda

|Silver

|2026

| Medical research – Tuberculosis and other respiratory diseases

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!scope="row"|Vukosi Marivate

|Silver

|2026

| Computer science

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